2-Fluoro-β-alanine, a previously unrecognized substrate for bile acid coenzyme A:Amino acid:N-acyltransferase from human liver-Reference-Cited by-同舟云学术

2-Fluoro-β-alanine, a previously unrecognized substrate for bile acid coenzyme A:Amino acid:N-acyltransferase from human liver

Published:1990-09 Issue:6 Volume:40 Page:1241-1246
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Johnson Martin R.,Barnes Stephen,Sweeny David J.,Diasio Robert B.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference22 articles.

1. Clinical pharmacology of 5-fluorouracil;Diasio;Clin Pharmacol,1989

2. (+)-α-Fluoro-β-alanine (FBAL), the main metabolite of 5-fluorouracil (FU) and its enantiomer;Duschinsky,1973

3. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile;Heggie;Cancer Res,1987

4. Metabolism of 5-fluorouracil to an N-cholyl-2-cholyl-2-fluoro-β-alanine conjugate: Previously unrecognized role for bile acids in drug conjugation;Sweeny,1987

5. N-Chenodeoxy-cholyl-2-fluoro-β-alanine. A biliary metabolite of 5-fluorouracil in humans;Sweeny;Drug Metab Dispos,1988

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