Selective inhibition of ribonucleotide reductase by the monofunctional alkylating agent 5(1-aziridinyl)-2,4-dinitrobenzamide (CB 1954)
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference23 articles.
1. 2,4-Dinitro-5-ethyleneiminobenzamide (CB 1954): A potent and selective inhibitor of the growth of the Walker carcinoma 256
2. Effects upon tumours of Various Haloalkylarylamines
3. Cytotoxicity of alkylating agents towards sensitive and resistant strains of Escherichia coli in relation to extent and mode of alkylation of cellular macromolecules and repair of alkylation lesions in deoxyribonucleic acids
4. Studies on the reversal of the selective antitumour effect of the aziridinyl derivative cb 1954 by 4-amino-5-imidazolecarboxamide
5. Protection against the effects of the antitumour agent CB 1954 by certain imidazoles and related compounds
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1. 3D Structure, Dimerization Modeling, and Lead Discovery by Ligand-protein Interaction Analysis of p60 Transcription Regulator Protein (p60TRP);Molecular Informatics;2015-07-20
2. CB 1954: From the Walker Tumor to NQO2 and VDEPT;Current Pharmaceutical Design;2003-10-01
3. The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT);Cancer and Metastasis Reviews;1993-06
4. Cytotoxicity and activation of CB1954 in a human tumour cell line;Biochemical Pharmacology;1991-05
5. Alkylating agents;The Chemistry of Antitumour Agents;1990
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