Pharmacological profile of inhibition of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein efflux in human HCT-8 intestinal epithelial cells

Author:

Collington Georgina K.,Allen Christopher N.,Simmons Nicholas L.,Hirst Barry H.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

1. Cytoplasmic pH and free Mg2+ in lymphocytes;Rink;J Cell Biol,1982

2. Renal cells on a Millipore microporous network—the use of BCECF to monitor plasma membrane integrity;Essig-Marcello;Toxicol In Vitro,1988

3. Measurement of cytotoxicity by target cell release and retention of the fluorescent dye bis-carboxyethyl-carboxyfluorescein (BCECF);Kobler;J Immunol Methods,1988

4. Efflux of bis-carboxyethyl-carboxyfluorescein(BCECF) by a novel ATP-dependent transport mechanism in epithelial cells;Allen;Biochem Biophys Res Commun,1990

5. Allen CN, Gray TJB, Harpur ES and Hirst BH, Comparison of LDH, 51Cr, and BCECF efflux as indices of non-steroidal anti-inflammatory drug-induced toxicity in human gastrointestinal (HGT-1, HCT-8 & T84) cell lines: BCECF efflux is not an index of plasma membrane integrity. Toxicol In Vitro, in press.

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