Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin-Reference-Cited by-同舟云学术

Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

Published:1989-08 Issue:16 Volume:38 Page:2677-2684
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Rosowsky Andre,Freisheim James H.,Hynes John B.,Queener Sherry F.,Bartlett Marilyn,Smith James W.,Lazarus Herbert,Modest Edward J.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference38 articles.

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2. 5-Benzyl-2,4-diaminopyrimidines as antibacterial agents. I. Synthesis and antibacterial activity;Roth;J Med Pharm Chem,1962

3. Clinical effects of the dichloro and monochlorophenyl analogues of diamino pyrimidine: antagonists of folic acid;Murphy;J Clin Invest,1954

4. Effect of the substituent at C-6 on the biological activity of 2,4-diamino-5-(1-adamantyl)pyrimidines;Jonak;J Med Chem,1973

5. Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts;Rosowsky;Biochem Pharmacol,1980

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