Chiral inversion of drug: Role of intestinal bacteria in the stereoselective sulphoxide reduction of flosequinan

Author:

Eiji Kashiyama,Tsuyoshi Yokoi,Takashi Todaka,Masaaki Odomi,Tetsuya Kamataki

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

1. Metabolism of foreign compounds by gastrointestinal microorganisms;Scheline;Pharmacol Rev,1973

2. Role of the gastrointestinal mucosa and microflora in the bioactivation of dietary and environmental mutagens or carcinogens;Chadwick;Drug Metab Rev,1992

3. The role of the gut flora in the reduction of sulphinpyrazone in the rat;Renwick;Biochem Pharmacol,1982

4. The role of the gut flora in the reaction of sulphoxide containing drugs;Renwick;Biochem Pharmacol,1986

5. The effect of BTS 49465 on blood pressure and peripheral arteriolar and venous tone in normal volunteers;Cowley;Hypertension,1984

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