Interaction of the aziridine moiety of RSU-1069 with nucleotides and inorganic phosphate
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference16 articles.
1. Radiation sensitization and chemopotentiation: Rsu 1069, a compound more efficient than misonidazole in vitro and in vivo
2. RSU 1069, a 2-nitroimidazole containing an alkylating group: High efficiency as a radio- and chemosensitizer in vitro and in vivo
3. Induction of DNA strand breaks by RSU-1069, a nitroimidazole-aziridine radiosensitizer
4. Photosensitive interaction of RSU 1069 with DNA
5. Alkylation reactions of mitomycin C at acid pH
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1. Overexpression of human NADPH:cytochrome c (P450) reductase confers enhanced sensitivity to both tirapazamine (SR 4233) and RSU 1069;British Journal of Cancer;1997-11
2. Hypoxia-specific cytotoxins in cancer therapy;Seminars in Radiation Oncology;1996-01
3. Synthesis and biological properties of carboranylaziridines bearing cascade polyols;Bioorganic & Medicinal Chemistry Letters;1996-01
4. Application of high-performance liquid chromatography for recognition of covalent nucleic acid modification with anticancer drugs;Journal of Chromatography B: Biomedical Sciences and Applications;1993-08
5. Induction of mutations in V79-4 mammalian cells under hypoxic and aerobic conditions by the cytotoxic 2-nitroimidazole-aziridines, RSU-1069 and RSU-1131;Biochemical Pharmacology;1992-10
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