NADPH-dependent enzyme-catalyzed reduction of aldophosphamide, the pivotal metabolite of cyclophosphamide

Author:

Parekh Hemant K.,Sladek Norman E.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference56 articles.

1. Metabolism of oxazaphosphorines;Sladek;Pharmacol Ther,1988

2. Sladek NE, Metabolism and pharmacokinetic behavior of cyclophosphamide and related oxazaphosphorines. In: Metabolism and Reactions of Anticancer Drugs (The International Encyclopedia of Pharmacology and Therapeutics) (Ed. Powis G), in press.

3. Metabolism of cyclophosphamide by sheep;Bakke;J Agric Food Chem,1972

4. Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide;Connors;Biochem Pharmacol,1974

5. Isolation and mass spectral identification of blood metabolites of cyclophosphamide: Evidence for phosphoramide mustard as the biologically active metabolite;Struck;Biomed Mass Spectrom,1975

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