The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-l,2,4-benzotriazine-l ,4-dioxide (SR 4233, WIN 59075) by mouse liver-Reference-Cited by-同舟云学术

The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-l,2,4-benzotriazine-l ,4-dioxide (SR 4233, WIN 59075) by mouse liver

Published:1992-07 Issue:2 Volume:44 Page:251-259
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Walton M.I.,Wolf C.R.,Workman P.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference43 articles.

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2. Enhancement of radiation-induced cell killing by the hypoxic cell toxin SR 4233;Zeman;Radiother Oncol,1988

3. Structure-activity relationships for benzotriazine di-N-oxides;Zeman;Int J Radial Oncol Biol Phys,1989

4. New drugs and novel agents;Workman;Curr Opinion Oncol,1989

5. Hypoxia in tumors: a paradigm for the approach to biochemical and physiologic heterogeneity;Coleman;J Natl Cancer Inst,1988

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