Kinetic properties of the metabolism of imipramine and desipramine in isolated rat hepatocytes

Author:

Chiba Masato,Fujita Shoichi,Suzuki Tokuji

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference19 articles.

1. The metabolism of drugs in isolated rat hepatocytes. A comparison with in vuivo drug metabolism and drug metabolism in subcellular liver fractions;Billings;Drug Metab Dispos,1977

2. Kinetic studies on the metabolism of ethylmorphine by isolated hepatocytes from adult rats;Erickson;Biochem Pharmacol,1976

3. Prediction of hepatic extraction ratio from m vitro measurement of intrinsic clearance;Rane;J Pharmacol Exp Ther,1977

4. N-Demethylation as an example of drug metabolism in isolated rat hepatocytes;Heyes;Biochem Pharmacol,1976

5. Influence of dose on first-pass kinetics of 14C-imipramine in the isolated perfused rat liver;Beaubien;Drug Metab Dispos,1979

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