Identification of 5-meta-Hydroxyphenyl-5-phenylhydantoin as a metabolite of diphenylhydantoin
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference13 articles.
1. Clinical and Electroencephalographic Correlations with Serum Levels of Diphenylhydantoin
2. Diphenylhydantoin Metabolism, Blood Levels, and Toxicity
3. Relationship Between the Plasma Level of Diphenylhydantoin Sodium and Its Cardiac Antiarrhythmic Effects
4. Insufficient parahydroxylation as a cause of diphenylhydantoin toxicity
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1. The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983;Drug Metabolism and Disposition;2008-03-05
2. Aqueous solubility and dissolution rate does not adequately predict in vivo performance: A probe utilizing some N‐acyloxymethyl phenytoin prodrugs;Journal of Pharmaceutical Sciences;1999-08
3. Metabolism of phenytoin and covalent binding of reactive intermediates in activated human neutrophils;Biochemical Pharmacology;1995-07
4. Two-dimensional high-performance liquid chromatographic method to assay p-hydroxyphenylphenylhydantoin enantiomers in biological fluids and stereoselectivity of enzyme induction in phenytoin metabolism;Journal of Chromatography B: Biomedical Sciences and Applications;1992-03
5. Stereoselective inhibition of diphenylhydantoin metabolism byp-hydroxyphenyl-phenylhydantoin enantiomers in rats;Chirality;1991
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