Antimalarial activity of a 4', 5'-unsaturated 5'- fluoroadenosine mechanism-based inhibitor of s-adenosyl-l-homocysteine hydrolase

Author:

Bitonti Alan J.,Baumann Russell J.,Jarvi Esa T.,McCarthy James R.,Mccann Peter P.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference19 articles.

1. The problem of drug resistance in malaria.;Peters;Parasitology,1985

2. Plasmodium falciparum: Antimalarial activity in culture of Sinefungin and other methylation inhibitors;Trager;Exp Parasitol,1980

3. Effects of two methylthioadenosine analogues, SIBA and deaza-SIBA, on P. falciparum-infected red cells;Whaun,1984

4. Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase;Ueland;Pharmacol Rev,1982

5. Antimalarial activity of neplanocin A with perturbations in the metabolism of purines, polyamines and S-adenosylmethionine;Whaun;J Pharmacol Exp Ther,1986

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