Restricted bioreductive metabolism of a nitroimidazole-thiadiazole derivative with curative action in experimental Trypanosoma cruzi infections

Author:

Tsuhako Maria H.,Alves Maria J.M.,Colli Walter,Brener Zigman,Augusto Ohara

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference36 articles.

1. 2-Amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole: a new antimicrobial agent;Berkelhammer;Science,1968

2. 2-Amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole, a new antimicrobial agent. VII. Action against subcutaneous Trichomonas vaginalis infections in mice;Burden,1969

3. 2-Amino-5(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole, a new antimicrobial agent. VIII. Antiamoebic activity in vivo of the hydrochloride salt;Carvajal,1969

4. 2-Amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole, a new antimicrobial agent. IX. Action against hemoflagellate infections in laboratory animals;Burden;Antimicrob Agents Chemother,1968

5. A nitroimidazole-thiadiazole derivative with curative action in experimental Trypanosoma cruzi infections;Filardi;Ann Trop Med Parasitol,1982

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