Metabolite complex formation of orphenadrine with cytochrome P450

Author:

Roos Peter H.,Mahnke Axel

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference59 articles.

1. Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture;Watkins;J Biol Chem,1986

2. Inducers of cytochrome P-450d: influence on microsomal catalytic activities and differential regulation by enzyme stabilization;Voorman;Arch Biochem Biophys,1988

3. Substrate-, hormone-, and cAMP-regulated cytochrome P450 degradation;Eliasson,1990

4. Mechanisms of inhibition of xenobiotic-metabolizing enzymes;Testa;Xenobiotica,1990

5. Selectivity in the inhibition of mammalian cytochromes P450 by chemical agents;Murray;Pharmacol Rev,1990

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