Histamine receptor-dependent and/or -independent activation of guanine nucleotide-binding proteins by histamine and 2-substituted histamine derivatives in human leukemia (HL-60) and human erythroleukemia (HEL) cells

Author:

Hagelüken Astrid,Grünbaum Lore,Klinker Jan F.,Nürnberg Bernd,Harhammer Rainer,Schultz Günter,Leschke Christian,Schunack Walter,Seifert Roland

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference35 articles.

1. Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization;Seifert;Naunyn Schmiedebergs Arch Pharmacol,1994

2. Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue;Seifert;Mol Pharmacol,1992

3. Reversible activation of NADPH oxidase in membranes of HL-60-leukemic cells;Seifert;Biochem Biophys Res Commun,1987

4. The H1receptor agonist, 2-(3-chlorophenyl)histamine, actives Gi-proteins in HL-60 cells through a mechanism which is independent of known histamine receptor subtypes;Seifert;Mol Pharmacol,1994

5. G proteins: transducers of receptor-generated signals;Gilman;Annu Rev Biochem,1987

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