Inactivation of chick embryo hepatic cytochrome P450 1A, 2H and 3A following in ovo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine and 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone

Author:

McNamee James P.,Kimmett Susan M.,Marks Gerald S.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference50 articles.

1. Suicidal destruction of cytochrome P-450 and reduction of ferrochelatase activity by 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine and its analogues in chick embryo liver cells;Marks;Mol Pharmacol,1985

2. Ferrochelatase-inhibitory activity and N-alkylprotoporphyrin formation with analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4, 6-trimethylpyridine (DDC) containing extended 4-alkyl groups: Implications for the active site of ferrochelatase;McCluskey;Mol Pharmacol,1986

3. Inactivation of cytochrome P450 and inhibition of ferrochelatase by analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine with 4-nonyl and 4-dodecyl substituents;McCluskey;Can J Physiol Pharmacol,1992

4. Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts;Correia;Arch Biochem Biophys,1987

5. N-Alkylation of the haem moiety of cytochrome P-450 caused by substituted dihydropyridines: Preferential attack of different pyrrole nitrogen atoms after induction of various cytochrome P-450 isoenzymes;De Matteis;Biochem J,1983

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