Kinetics of human thrombin inhibition by two novel peptide inhibitors (Hirunorm IV and Hirunorm V)

Author:

Cappiello Mario,Vilardo Pier Giuseppe,Lippi Annalisa,Criscuoli Marco,Corso Antonella Del,Mura Umberto

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

1. Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile;Tapparelli;TIPS,1993

2. Thrombin;Lundblad,1976

3. Thrombin specificity;Fenton;Ann NY Acad Sci,1981

4. Anion-binding exosite of human α-thrombin and fibrin(ogen) recognition;Fenton;Biochemistry,1988

5. The refined 1.9-Angstrom X-ray crystal structure of D-Phe-Pro-Arg-Chloromethylketone-inhibited human α-thrombin—Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationship;Bode;Protein Sci,1992

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