Comparison of methotrexate polyglutamylation in l1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor

Author:

Spinella Michael J.,Brigle Kevin E.,Freemantle Sarah J.,Sierra Esteban E.,Goldman I.David

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference55 articles.

1. Antifolates: The next generation;Fleming,1992

2. The basis of antifolate cytoxicity, selectivity and metabolic transformations: Effects on utilization of endogenous and exogenous folate cofactors;Matherly,1994

3. Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia;Trippett;Blood,1992

4. Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia;Matherly;Blood,1995

5. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease;Göker;Leukemia,1993

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