A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats

Author:

Lubet Ronald A.,Nims Raymond W.,Dragnev Konstantin H.,Jones Collins R.,Diwan Bhalchandra A.,Devor Deborah E.,Ward Jerrold M.,Miller mark S.,Rice Jerry M.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference55 articles.

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2. P-450 genes: Structure, evolution and regulation;Nebert;Annu Rev Biochem,1987

3. The molecular biology of cytochrome P450s;Gonzalez;Pharmacol Rev,1988

4. Phenobarbital: Interactions with other drugs;Kutt,1989

5. Preparation of monospecific antibodies against two forms of rat liver cytochrome P-450 and quantitation of these antigens in microsomes;Thomas;Arch Biochem Biophys,1979

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