Participation of the CYP2D subfamily in lidocaine 3-hydroxylation and formation of a reactive metabolite covalently bound to liver microsomal protein in rats
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference14 articles.
1. Evidence for two catalytically different binding sites of liver microsomal cytochrome P-450: importance for species differences in oxidation pattern of lidocaine;von Bahr;Acta Pharmacol Toxicol,1977
2. Age associated alteration of lidocaine metabolism is position selective;Fujita;Biochem Biophys Res Commun,1985
3. Simultaneous quantitation of lidocaine and its four metabolites by high-performance liquid chromatography: application to studies on in vitro and in vivo metabolism of lidocaine in rats;Kawai;J Pharm Sci,1985
4. A new lidocaine metabolite, ω-diethylamino-2-hydroxymethyl-6-methylacetanilide;Kawai;Drug Metab Dispos,1986
5. Metabolism of lidocaine by purified rat liver cytochrome P-450 isozymes;Oda;Biochem Pharmacol,1989
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