The enzymology of doxorubicin quinone reduction in tumour tissue

Author:

Cummings Jeffrey,Allan Lucy,Willmott Neville,Riley Robert,Workman Paul,Smyth John F.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference41 articles.

1. Generation of free radicals of quinone groups containing anti-cancer chemicals in NADPH-microsome systems as evidenced by initiation of sulfite oxidation;Handa;Can,1975

2. Daunomycin and adriamycin metabolism via reductive glycosidic cleavage;Asbell;J Pharmacol Exp Ther,1972

3. Structure-activity relationships among Daunorubicin and Adriamycin analog;Henry;Cancer Treat Rep,1979

4. Doxorubicin (adriamycin): a critical review of free radical mechanisms of cytotoxicity;Keizer;Pharmacol Ther,1990

5. Free radicals and anticancer drug resistance: oxygen free radicals in the mechanism of drug cytotoxicity and resistance by certain tumors;Sinha;Free Rad Biol Med,1990

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