Demonstration of a direct effect on hepatic acyl CoA:cholesterol acyl transferase (ACAT) activity by an orally administered enzyme inhibitor in the hamster-Reference-Cited by-同舟云学术

Demonstration of a direct effect on hepatic acyl CoA:cholesterol acyl transferase (ACAT) activity by an orally administered enzyme inhibitor in the hamster

Published:1994-04 Issue:9 Volume:47 Page:1545-1551
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Burrier Robert E.,Deren Susan,McGregor Daniel G.,Hoos Lizbeth M.,Smith April A.,Davis Harry R.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. Role of acyl-CoA:cholesterol acyltransferase in cellular cholesterol metabolism;Suckling;J Lipid Res,1985

2. Therapeutic potential of ACAT inhibitors as lipid lowering and anti-atherosclerotic agents;Sliskovic;Trends Pharmacol Sci,1991

3. Hepatic ACAT activity in African green monkeys is highly correlated to plasma LDL cholesteryl ester enrichment and coronary artery atherosclerosis;Carr;Arterioscler Thromb,1992

4. In vivo evidence that the lipid-regulating activity of the ACAT inhibitor CI-976 in rats is due to inhibition of both intestinal and liver ACAT;Krause;J Lipid Res,1993

5. An acyl CoA:cholesterol-O-acyltransferase inhibitor with hypocholesterolemic activity;DeVries;J Med Chem,1986

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