DNA damaging effects and voltammetric studies on the hypoxic cell toxin 3-amino-1,2,4-benzotriazine-1,4-dioxide, SR4233, as a function of pH

Author:

Tocher Joanne H.,Virk Narinder S.,Edwards David I.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference14 articles.

1. Hypoxic cell radiosensitizers: where next?;Brown;Int J Radial Oncol Biol Phys,1989

2. SR4233: a new bioreductive agent with high selective toxicity for hypoxic cells;Zeman;Int J Radiat Oncol Biol Phys,1986

3. Pre- and post-irradiation radiosensitization by SR4233;Zeman;Int J Radiat Oncol Biol Phys,1989

4. Molecular mechanisms for the hypoxia dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR4233);Laderoute;Biochem Pharmacol,1988

5. Comparative DNA damage induced by nitroimidazole-aziridine drugs: I. Effects of methyl substitution on drug action;Dale;Anti-Cancer Drug Design,1988

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