Fast mutual exclusivity algorithm nominates potential synthetic lethal gene pairs through brute force matrix product computations-Reference-Cited by-同舟云学术

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Fast mutual exclusivity algorithm nominates potential synthetic lethal gene pairs through brute force matrix product computations

Published:2021 Issue: Volume:19 Page:4394-4403
ISSN:2001-0370
Container-title:Computational and Structural Biotechnology Journal
language:en
Short-container-title:Computational and Structural Biotechnology Journal

Author:

Fedrizzi Tarcisio,Ciani Yari,Lorenzin Francesca,Cantore Thomas,Gasperini Paola,Demichelis Francesca

Funder

Horizon 2020

Prostate Cancer Foundation

Foundation for Alcohol Research and Education

Horizon 2020 Framework Programme

European Research Council

Ministero dell’Istruzione, dell’Università e della Ricerca

National Cancer Institute

NCI

Publisher

Elsevier BV

Subject

Computer Science Applications,Genetics,Biochemistry,Structural Biology,Biophysics,Biotechnology

Reference61 articles.

1. Synthetic lethality and cancer;O'Neil;Nat Rev Genet,2017

2. Genetics of natural populations; recombination and variability in populations of Drosophila pseudoobscura;Dobzhansky;Genetics,1946

3. Integrating genetic approaches into the discovery of anticancer drugs;Hartwell;Science,1997

4. The concept of synthetic lethality in the context of anticancer therapy;Kaelin;Nat Rev Cancer,2005

5. Synthetic lethality as an engine for cancer drug target discovery;Huang;Nat Rev Drug Discov,2020

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1. ASTER: A Method to Predict Clinically Relevant Synthetic Lethal Genetic Interactions;IEEE Journal of Biomedical and Health Informatics;2024-03

2. Adaptation of a mutual exclusivity framework to identify driver mutations within oncogenic pathways;The American Journal of Human Genetics;2024-02

3. Adaptation of a Mutual Exclusivity Framework to Identify Driver Mutations within Biological Pathways;2023-09-22

4. Epistasis and evolutionary dependencies in human cancers;Current Opinion in Genetics & Development;2022-12

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