DeepSP: Deep learning-based spatial properties to predict monoclonal antibody stability

Author:

Kalejaye Lateefat,Wu I-En,Terry Taylor,Lai Pin-Kuang

Funder

Stevens Institute of Technology

Publisher

Elsevier BV

Reference54 articles.

1. Computational tool for the early screening of monoclonal antibodies for their viscosities;Agrawal;MAbs,2016

2. Design of therapeutic proteins with enhanced stability;Chennamsetty;Proc Natl Acad Sci,2009

3. Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions;Bhambhani;J Pharm Sci,2012

4. Challenges in the development of high protein concentration formulations;Shire;J Pharm Sci,2004

5. Evaluation of the impact of viscosity, injection volume, and injection flow rate on subcutaneous injection tolerance;Berteau;Med Devices (Auckl,2015

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