Inhibitors of sterol synthesis. Effects of dietary 5α-cholest-8(14)-en-eβ-ol-15-one on early enzymes in hepatic cholesterol biosynthesis
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Organic Chemistry,Molecular Biology,Biochemistry
Reference49 articles.
1. Inhibition of sterol biosynthesis in L cells and mouse liver cells by 15-oxygenated sterols.
2. 14 alpha-Ethyl-5 alpha-cholest-7-ene-3 beta,15 alpha-diol, a potent inhibitor of sterol biosynthesis, has two sites of action in cultured mammalian cells.
3. Inhibitors of sterol synthesis. Hypocholesterolemic action of dietary 5α-cholest-8(14)-en-3β-ol-15-one in rats and mice
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1. Oxysterols: Modulators of Cholesterol Metabolism and Other Processes;Physiological Reviews;2000-01-01
2. Sterol synthesis. Synthesis of 3β-hydroxy-25,26,26,26,27,27,27-heptafluorocholest-5-en-7-one and its effects on HMG-CoA reductase activity in Chinese hamster ovary cells, on ACAT activity in rat jejunal microsomes, and serum cholesterol levels in rats;Chemistry and Physics of Lipids;1998-08
3. Review of progress in sterol oxidations: 1987–1995;Lipids;1996-05
4. Irreversible inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from yeast by F-244 and (RS)-β-butyrolactone;Canadian Journal of Chemistry;1996-01-01
5. Inhibitors of sterol synthesis. Metabolism-based design and construction of a new analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects in cultured mammalian cells and in rats.;Journal of Lipid Research;1995-04
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