Inhibitors of sterol synthesis. Concerning the structure of 15β-methyl-5α,14β-cholest-7-ene-3β,15α-diol, an inhibitor of cholesterol biosynthesis
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Organic Chemistry,Molecular Biology,Biochemistry
Reference31 articles.
1. Inhibition of sterol biosynthesis in L cells and mouse liver cells by 15-oxygenated sterols.
2. 14.alpha.-Ethyl-5.alpha.-cholest-7-ene-3.beta.,15.alpha.-diol, an extraordinarily potent inhibitor of sterol biosynthesis in animal cells
3. Inhibition of sterol biosynthesis in animal cells by 14 alpha-alkyl-substituted 15-oxygenated sterols.
4. Inhibition of sterol biosynthesis by 9α-fluoro and 9α-hydroxy derivatives of 5α-cholest-8(14)-en-3β-ol-15-one
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Oxysterols: Modulators of Cholesterol Metabolism and Other Processes;Physiological Reviews;2000-01-01
2. Review of progress in sterol oxidations: 1987–1995;Lipids;1996-05
3. Inhibitors of sterol synthesis: effects of a 7α-alkyl analog of 3β-hydroxy-5α-cholest-8(14)-en-15-one on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells and on serum cholesterol levels and other parameters in rats;Chemistry and Physics of Lipids;1994-04
4. Inhibitors of sterol synthesis. Characterization of beta,gamma-unsaturated analogs of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.;Journal of Lipid Research;1991-07
5. Analysis of Oxysterols;Analysis of Sterols and Other Biologically Significant Steroids;1989
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