Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715)

Author:

Layer Richard T.,Popik Piotr,Olds Tia,Skolnick Phil

Publisher

Elsevier BV

Subject

Behavioral Neuroscience,Biological Psychiatry,Clinical Biochemistry,Pharmacology,Toxicology,Biochemistry

Reference52 articles.

1. Inhibition of rat brain monoamine oxidase activity by cerebral anti-ischemic agent, ifenprodil;Arai;Neuropharmacology,1991

2. Ifenprodil and SL 82. 0715 as cerebral antischemic agents. II. Evidence for N-ethyl-d-aspartate receptor antagonist properties;Carter;J. Pharmacol. Exp. Ther.,1988

3. Ifenprodil and SL 82. 0715 are antagonists at the polyamine site of the N-methyl-d-aspartate (NMDA) receptor;Carter;Eur. J. Pharmacol.,1989

4. Seperation of α1 adrenergic and N-methyl-d-aspartate antagonist activity in a series of ifenprodil compounds;Chenard;J. Med. Chem.,1991

5. Ifenprodil and SL 82. 0715 potently inhibit binding of [3H](+)-3-PPP to σ binding sites in rat brain;Contreras;Neurosci. Lett.,1990

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