The differential activities of R(+)- and S(−)-zacopride as 5-HT3 receptor antagonists

Author:

Barnes J.M.,Barnes N.M.,Costall B.,Domeney A.M.,Johnson D.N.,Kelly M.E.,Munson H.R.,Naylor R.J.,Young R.

Publisher

Elsevier BV

Subject

Behavioral Neuroscience,Biological Psychiatry,Clinical Biochemistry,Pharmacology,Toxicology,Biochemistry

Reference31 articles.

1. Zacopride (AHR11190B): A unique and potent gastrointestinal prokinetic and anti-emetic agent in laboratory animals;Alphin;Dig. Dis. Sci.,1986

2. Neuropharmacology of emesis induced by anticancer drugs;Andrews;Trends Pharmacol. Sci.,1988

3. Identification and characterisation of 5-hydroxytryptamine3 recognition sites in human brain tissue;Barnes;J. Neurochem.,1989

4. 5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue;Barnes;Nature,1989

5. GR38032F improves performance in a mouse habituation test, and inhibits cholinergic linked deficits;Barnes;Br. J. Pharmacol.,1989

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