The defects in all classes of aryl hydrocarbon hydroxylase-deficient mutant of mouse hepatoma line, Hepa-1, are restricted to activities catalyzed by cytochrome P-450
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference20 articles.
1. Structural gene products of the Ah locus: Evidence for many unique P-450 mediated monooxygenase activities reconstituted from 3-methylcholanthrene-treated C57BL6N mouse liver microsomes;Lang;J. Biol. Chem.,1981
2. Genetic differences in the induction of monooxygenase activities by polycyclic aromatic compounds;Nebert;Pharmacol. Ther.,1979
3. Regulatory gene product of the Ah locus: Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation;Okey;J. Biol. Chem.,1979
4. Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase;Hankinson,1979
5. Evidence that benzo(a)pyrene-resistant aryl hydrocarbon hydroxylase-deficient variants of mouse hepatoma line Hepa-1, are mutational in origin;Hankinson;Somat. Cell Genet.,1981
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Genetic and molecular analysis of the Ah receptor and of Cyp1a1 gene expression;Biochimie;1991-01
2. Molecular Mechanisms in Protection Against Carcinogenesis;Cancer Biology and Therapeutics;1987
3. On the mechanisms of induction of cancer-protective enzymes: a unifying proposal.;Proceedings of the National Academy of Sciences;1985-12-01
4. Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1 cell line.;Journal of Biological Chemistry;1985-02
5. Isolation and characterization of revertants from four different classes of aryl hydrocarbon hydroxylase-deficient hepa-1 mutants.;Molecular and Cellular Biology;1984-08
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