Studies on the mutagenic activation of heterocyclic amines by cynomolgus monkey, rat and human microsomes show that cynomolgus monkeys have a low capacity to N-oxidize the quinoxaline-type heterocyclic amines-Reference-Cited by-同舟云学术

Studies on the mutagenic activation of heterocyclic amines by cynomolgus monkey, rat and human microsomes show that cynomolgus monkeys have a low capacity to N-oxidize the quinoxaline-type heterocyclic amines

Published:1993-09 Issue:2-3 Volume:73 Page:95-104
ISSN:0304-3835
Container-title:Cancer Letters
language:en
Short-container-title:Cancer Letters

Author:

Davis Cindy D.,Adamson Richard H.,Snyderwine Elizabeth G.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference33 articles.

1. Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates;Adamson,1991

2. Activation of the food mutagens IQ and MeIQ by hepatic S9 fractions derived from various species;Alldrick;Mutat. Res.,1985

3. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test;Ames;Mutat. Res.,1975

4. Mutagenic potency of heterocyclic amines towards Salmonella typhimurium: possible causes of variability in the results observed;Brams;Mutat. Res.,1992

5. Human cytochrome P450PA (P-4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of the carcinogenic arylamines;Butler,1989

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