Effects of age and ethanol on DNA single-strand breaks and toxicity induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone or n-nitrosodimethylamine in hamster and rat liver

Author:

Jorquera R.,Castonguay A.,Schuller H.M.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference38 articles.

1. Tissue levels and biological effects of N-nitrosodimethylamine in mice during chronic low or high dose exposure with or without ethanol;Anderson;Drug Metab. Dispos.,1986

2. Repressible and inducible enzymic forms of dimethylnitrosamine-demethylase;Arcos;Z. Krebsforsch.,1977

3. Modulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-demethylation and denitrosation by rat liver microsomes;Castonguay;Cancer Lett.,1991

4. Modulation of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by hamster liver microsomes to protein alkylating species;Castonguay;Toxicol. in Vitro,1992

5. Brief communication: age-dependence of hepatic dimethylnitrosamine-demethylase activity in the rat;Davies;J. Natl. Cancer Inst.,1976

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