Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea

Author:

Scherer E.,Van Den Berg T.,Vermeulen E.,Winterwerp H.H.K.,Den Engelse L.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference37 articles.

1. Esophageal microsomal metabolism of N-nitrosomethyl-benzylamine in the zinc-deficient rat;Barch;Cancer Res.,1984

2. Histopathology of methylbenzylnitrosamine-induced esophageal carcinoma in the rat: Comparison with cytomorphology;Barch;J. Natl. Cancer Inst.,1986

3. Cell specificity in hepatocarcinogenesis: Preferential accumulation of O6-methylguanine in target cell DNA during continous exposure of rats to 1,2-dimethylhydrazine;Bedell;Cancer Res.,1982

4. Genetic evidence for excision repair of O6-alkylguanine in mammalian cells;Boyle;J. Cell Sci. Suppl.,1987

5. Effect of the esophageal carcinogen methylbenzylnitrosamine and of a putative potentiating factor, a trichothecene mycotoxin, on O6-methylguanine-DNA methyl transferase in rat esophagus and liver;Craddock;Cancer Lett.,1987

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