Metabolic activation of mutagenic tryptophan pyrolysis products (Trp-P-1 and Trp-P-2) by a purified cytochrome P-450-dependent monooxygenase system

Author:

Ishii Kenji,Ando Mebae,Kamataki Tetsuya,Kato Ryuichi,Nagao Minako

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference14 articles.

1. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsomes mutagenicity test;Ames;Mutat. Res.,1975

2. Conversion of P-450 to P-420 by neutral salts and some other reagents;Imai;Eur. J. Biochem.,1967

3. A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits;Imai;Biochem. Biophys. Res. Commun.,1974

4. Studies on the metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) and benzphetamine using an apparently homogeneous preparation of rat liver cytochrome P-450 Effect of cytochrome P-450 antibody preparation;Kamataki;Mol. Pharmacol.,1976

5. The involvement of cytochrome P-448 and P-450 in NADH-dependent O-demethylation of p-nitro-anisole in rat liver microsomes;Kamataki;Jpn. J. Pharmacol.,1979

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