Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Author:

Reen Rashmeet K.,Wiebel Friedrich J.,Singh Jaswant

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference33 articles.

1. Piperine, a plant alkaloid of the piper species, enhances the bioavailability of aflatoxin B1 in rat tissues;Allameh;Cancer Letters,1992

2. Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1;Aoyama,1990

3. Biochemical basis of enhanced drug bioavailability by piperine: Evidence that piperine is a potent inhibitor of drug metabolism;Atal;Journal of Pharmacology and Experimental Therapeutics,1985

4. The role of glutathione and glutathione-S-transferases in metabolism of chemical carcinogens and other electrophillic agents;Chasseaud;Advances in Cancer Research,1979

5. The development of a human cell line stable expressing human CYP3A4: Role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and;Crespi;Carcinogenesis,1991

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