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Phenylethylene glycol-derived LpxC inhibitors with diverse Zn2+-binding groups

  • Published:2019-01 Issue:4 Volume:75 Page:486-509
  • ISSN:0040-4020
  • Container-title:Tetrahedron
  • language:en
  • Short-container-title:Tetrahedron

Author:

Galster Magdalena,Löppenberg Marius,Galla Fabian,Börgel Frederik,Agoglitta Oriana,Kirchmair Johannes,Holl Ralph

Funder

Apothekerstiftung Westfalen-Lippe

Deutsche Forschungsgemeinschaft

Bergen Research Foundation

DZIF

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference73 articles.

1. Drug Design of Zinc-enzyme Inhibitors: Functional, Structural, and Disease Applications;Supuran,2009

2. Emerging trends in metalloprotein inhibition;Rouffet;Dalton Trans.,2011

3. Identifying chelators for metalloprotein inhibitors using a fragment-based approach;Jacobsen;J. Med. Chem.,2011

4. Targeting metalloenzymes: a strategy that works;White;Curr. Opin. Pharmacol.,2003

5. Insights into the zinc-dependent deacetylase LpxC: biochemical properties and inhibitor design;Kalinin;Curr. Top. Med. Chem.,2016

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