A facile tandem double-dehydrative-double-Heck olefination strategy for pot-economic synthesis of ( E )-distyrylbenzenes as multi-target-directed ligands against Alzheimer's disease employing C. elegans model
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference86 articles.
1. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics;Hardy;Science,2002
2. A century of Alzheimer's disease;Goedert;Science,2006
3. Cholinesterase inhibitors for the treatment of Alzheimer's disease: getting on and staying on;Grossberg;Curr Ther Res Clin Exp,2003
4. Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - too little activation is bad, too much is even worse;Parsons;Neuropharmacology,2007
5. In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers;Nesterov;Angew Chem Int Ed,2005
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Medicinal chemistry perspective on the structure–activity relationship of stilbene derivatives;RSC Advances;2024
2. Synthesis, Structures, and Aggregation-Induced Emission Properties of Distyrylbenzene Derivatives Containing Fluorine Groups;The Journal of Organic Chemistry;2023-10-09
3. Review on the recent development on ionic liquid promoted domino reactions in synthesis of eco-compatible and complex molecules;Journal of Ionic Liquids;2023-06
4. The multitarget approach as a green tool in medicinal chemistry;Contemporary Chemical Approaches for Green and Sustainable Drugs;2022
5. Exploration of Potent Multi-target-directed-ligands as Anti-alzheimer’s Disease Agents: A Moiety Based Review;Mini-Reviews in Medicinal Chemistry;2021-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3