Synthesis of cell-permeable stapled BH3 peptide-based Mcl-1 inhibitors containing simple aryl and vinylaryl cross-linkers-Reference-Cited by-同舟云学术

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Synthesis of cell-permeable stapled BH3 peptide-based Mcl-1 inhibitors containing simple aryl and vinylaryl cross-linkers

Published:2014-10 Issue:42 Volume:70 Page:7740-7745
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Muppidi Avinash,Doi Kenichiro,Ramil Carlo P.,Wang Hong-Gang,Lin Qing

Funder

Pardee Foundation

Oishei Foundation

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

1. The Challenge of Drugging Undruggable Targets in Cancer: Lessons Learned from Targeting BCL-2 Family Members

2. Drug Discovery Research;Yin,2006

3. Helical peptides with three pairs of Asp-Arg and Glu-Arg residues in different orientations and spacings

4. Stabilization of Helical Domains in Short Peptides Using Hydrophobic Interactions

5. Cation-pi interactions in structural biology

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1. Stapled peptides: targeting protein-protein interactions in drug development;Exploration of Drug Science;2024-04-18

2. Synthesis and optimization of stapled DOCK peptides with improved drug-like properties;Arkivoc;2024-03-10

3. Macrocyclic Peptides Closed by a Thioether–Bipyridyl Unit That Grants Cell Membrane Permeability;ACS Bio & Med Chem Au;2023-08-13

4. Targeting peptide‐mediated interaction between the N‐protein and P‐protein of human pediatric respiratory syncytial virus by molecular design of chemically stapled helical peptides;Journal of the Chinese Chemical Society;2023-07-18

5. Maleimide constrained BAD BH3 domain peptides as BCL-xL Inhibitors: A versatile approach to rapidly identify sites compatible with peptide constraining;Bioorganic & Medicinal Chemistry Letters;2023-05

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