Design and synthesis of novel 5,6-bisindolylpyrimidin-4-ones structurally related to ruboxistaurin (LY333531)-Reference-Cited by-同舟云学术

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Design and synthesis of novel 5,6-bisindolylpyrimidin-4-ones structurally related to ruboxistaurin (LY333531)

Published:2010-12 Issue:51 Volume:66 Page:9754-9761
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Pierce Larry T.,Cahill Michael M.,McCarthy Florence O.

Funder

Irish Research Council for Science, Engineering and Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

1. Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

2. Isolation and structure of rebeccamycin - a new antitumor antibiotic from nocardia aerocoligenes

3. Signalling targets for anticancer drug development

4. A new alkaloid AM-2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization.

5. Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

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1. Bisindolyl Maleimides and Indolylmaleimide Derivatives—A Review of Their Synthesis and Bioactivity;Pharmaceuticals;2023-08-22

2. Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition;Bioorganic & Medicinal Chemistry;2018-08

3. C(2)-Functionalization of pyrimidin-4(3H)-one derivatives in the synthesis of its biologically active derivatives;Russian Chemical Bulletin;2015-11

4. Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents;European Journal of Medicinal Chemistry;2012-10

5. New Efficient Synthesis of 2,3,5-Trisubstituted Pyrimidin-4(3H)-ones from Baylis–Hillman Adducts;Synthesis;2012-08-08

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