First enantioselective synthesis of the novel antiinfective TAN-1057A via its aminomethyl-substituted dihydropyrimidinone heterocycle

Author:

Belov Vladimir N.,Brands Michael,Raddatz Siegfried,Krüger Jochen,Nikolskaya Sofia,Sokolov Viktor,de Meijere Armin

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference22 articles.

1. TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity.

2. A new anti-MRSA dipeptide, TAN-1057 A

3. Total Synthesis of the Anti Methicillin-Resistant Staphylococcus aureus Peptide Antibiotics TAN-1057A-D

4. Synthesis and Antimicrobial Evaluation of TAN-1057A/B Analogs.

5. Brands, M.; Es-Sayed, M.; Häbich, D.; Raddatz, S.; Krüger, J.; Endermann, R.; Gahlmann, R.; Kroll, H.- P.; Geschke, F.- U.; de Meijere, A.; Belov, V. N.; Sokolov, V. V.; Kozhushkov, S. I.; Kordes, M. TAN-1057 Derivatives. WO 00/12484.

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