An efficient and versatile synthesis of GlcNAcstatins—potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1,2-a]pyridine scaffold
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference39 articles.
1. Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc.
2. O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
3. Dynamic O-Glycosylation of Nuclear and Cytosolic Proteins
4. A Single Nucleotide Polymorphism in MGEA5 Encoding O-GlcNAc–selective N-Acetyl-β-d Glucosaminidase Is Associated With Type 2 Diabetes in Mexican Americans
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1. Carbohydrates and Carbohydrate‐Based Therapeutics in Alzheimer's Disease;Carbohydrate‐Based Therapeutics;2023-09-05
2. Protein O-GlcNAcylation in Cardiac Pathologies: Past, Present, Future;Frontiers in Endocrinology;2019-01-15
3. O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry;ACS Chemical Biology;2018-04-11
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5. Chemical tools to probe cellular O-GlcNAc signalling;Biochemical Journal;2013-10-24
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