Studies on the synthesis of a hindered analogue of the antitumour agent CC-1065
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference36 articles.
1. CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism.
2. CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.
3. Preliminary toxicity studies with the DNA-binding antibiotic, CC-1065.
4. Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice
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