A one-pot chemoenzymatic synthesis of (2S, 4R)-4-methylproline enables the first total synthesis of antiviral lipopeptide cavinafungin B
Author:
Funder
The Scripps Research Institute
Farris Foundation
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference38 articles.
1. Cyclic Colisporifungin and Linear Cavinafungins, Antifungal Lipopeptides Isolated from Colispora cavincola
2. Fellutamides A and B, cytotoxic peptides from a marine fish-possessing fungus Penicillium fellutanum
3. Isolation, Structure, and Biological Activities of Fellutamides C and D from an Undescribed Metulocladosporiella (Chaetothyriales) Using the Genome-Wide Candida albicans Fitness Test
4. The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase
5. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses
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