Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage

Author:

Adegoke E.O.,Xue Wang,Machebe N.S.,Adeniran S.O.,Hao Wang,Chen Wang,Han Zhang,Guixue Zhang,Peng Zheng

Funder

National Key R & D Program of China

Heilongjiang Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pollution,General Medicine

Reference80 articles.

1. Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway;Adegoke;Environ. Toxicol. Pharm.,2018

2. Selenium (Na2SeO3) upregulates expression of immune genes and blood-testis-barrier constituent proteins of bovine Sertoli cell in Vitro;Adegoke;Biol. Trace Elem. Res.,2018

3. Antioxidant systems and oxidative stress in the testes;Aitken;Oxid. Med. Cell Longev.,2008

4. Sertoli cells initiate testicular innate immune responses through TLR activation;Anna;J. Immunol.,2006

5. Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines;Blum;Am. J. Physiol.,1997

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