Long-term di-(2-ethylhexyl) phthalate exposure reduces sorafenib treatment efficacy by enhancing mesenchymal transition in hepatocellular carcinoma

Author:

Shih Ming-Syuan,Suk Fat-Moon,Chiu Wan-Chun,Lee Chun-Ya,Hsu Fang-Yu,Liao Yi-Jen

Funder

Ministry of Science and Technology, Taiwan

National Science and Technology Council

Office of Research and Development, Taipei Medical University

Taipei Municipal Wan-Fang Hospital

Publisher

Elsevier BV

Reference48 articles.

1. ATSDR. (2022). CHAPTER 7 REGULATIONS AND GUIDELINES. In Toxicological Profile for Di(2-Ethylhexyl)Phthalate (DEHP). Atlanta (GA).

2. Sorafenib in the treatment of advanced hepatocellular carcinoma;Ben Mousa;Saudi J. Gastroenterol.,2008

3. The effects of phthalate ester exposure on human health: a review;Chang;Sci. Total Environ.,2021

4. Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells;Chen;Oncotarget,2018

5. Potential molecular, cellular and microenvironmental mechanism of sorafenib resistance in hepatocellular carcinoma;Chen;Cancer Lett.,2015

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