Dimethyl sulfoxide/propylene glycol is a suitable solvent for the delivery of diazepam from osmotic minipumps

Author:

Arnot Michelle I.,Bateson Alan N.,Martin Ian L.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference8 articles.

1. Osmotic mini-pumps: A convenient program for weight-adjusted filling concentrations;Greenshaw;Br Res Bull,1986

2. Desensitization of adenosine A-2 receptors in striatum of the rat following chronic treatment with diazepam;Hawkins;Neuropharm,1988

3. Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils;Löscher;Pharmacol Biochem Behav,1986

4. Chronic administration of FG 7142 via continuous i.c.v. infusion increases GABAergic function;Marley;Neuropharm,1991

5. Chronic benzodiazepine administration I. Tolerance is associated with benzodiazepine receptor downregulation and decreased γ-aminobutyric acidA receptor function;Miller;J Pharm Exp Ther,1988

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