Interaction of the small-molecule kinase inhibitors tofacitinib and lapatinib with membranes

Author:

Haralampiev Ivan,Alonso de Armiño Diego Javier,Luck Meike,Fischer Markus,Abel Tobias,Huster Daniel,Di Lella Santiago,Scheidt Holger A.,Müller Peter

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Cell Biology,Biochemistry,Biophysics

Reference54 articles.

1. A historical overview of protein kinases and their targeted small molecule inhibitors;Roskoski;Pharm. Res.,2015

2. Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes;Roskoski;Pharm. Res.,2016

3. Small-molecule kinase inhibitors: an analysis of FDA-approved drugs;Wu;Drug Discov. Today,2016

4. Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin;Fresta;Bioorg. Med. Chem.,2002

5. A systematic analysis of physicochemical and ADME properties of all small molecule kinase inhibitors approved by US FDA from January 2001 to October 2015;O’Brien;Curr. Med. Chem.,2017

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