A Possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier

Author:

Št’astný M.,Strohalm J.,Plocová D.,Ulbrich K.,Řı́hová B.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference38 articles.

1. The biochemistry of P-glycoprotein-mediated multidrug resistance;Endicott;Annu Rev Biochem,1989

2. How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture;Gottesman;Cancer Res,1993

3. Myeloid and lymphoid cell alterations in normal mice exposed to chemotherapy with doxorubicin and/or the multidrug-resistance reversing agent SDZ PSC 833;Froidevaux;Int J Cancer,1994

4. Expression of a multidrug-resistance gene in human tumors and tissues;Fojo;PNAS USA,1987

5. Polymer–drug conjugates: potential for improved chemotherapy;Duncan;Anti-Cancer Drugs,1992

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