Circulating levels of the components of the GH/IGF-1/IGFBPs axis total and intact IGF-binding proteins (IGFBP) 3 and IGFBP 4 and total IGFBP 5, as well as PAPPA, PAPPA2 and Stanniocalcin-2 levels are not altered in response to energy deprivation and/or metreleptin administration in humans

Author:

Pilitsi Eleni,Peradze Natia,Perakakis Nikolaos,Mantzoros Christos S.

Funder

NIH

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference33 articles.

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2. Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men;Hartman;J Clin Endocrinol Metab,1992

3. Short-term fasting suppresses leptin and (conversely) activates disorderly growth hormone secretion in midluteal phase women—a clinical research center study;Bergendahl;J Clin Endocrinol Metab,1999

4. Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans;Chan;Proc Natl Acad Sci U S A,2006

5. Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states;Chan;J Clin Endocrinol Metab,2008

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