C26-analogs of naturally occurring bile alcohols-II. Preparation of 24-nor-5β-cholestane-3α,7α,12α,23-tetrols (23R and 23S) and 24-nor-5β-cholestane-3α,7α,12α,26-tetrols (25R and 25S) by a hydroboration procedure
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry
Reference11 articles.
1. Oxidation of 5beta-Cholestane-3alpha, 7alpha, 12alpha-triol by Rat Liver Microsomes
2. Bile alcohol metabolism in man. Conversion of 5beta-cholestane-3alpha, 7alpha,12alpha, 25-tetrol to cholic acid.
3. A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat.
4. C26-Analogs of naturally occurring C27 bile alcohols
5. Preparation of 24(R)- and 24(S)-5β-cholestane-3α,7α,24-triols and 25(R)- and 25(S)-5β-cholestane-3α,7α,26-triols by a hydroboration procedure
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1. Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure−Activity Relationship of a Series of Body and Side Chain Modified Analogues of Chenodeoxycholic Acid;Journal of Medicinal Chemistry;2004-07-23
2. Anomalous enantioselectivity in the sharpless asymmetric dihydroxylation reaction of 24-nor-5β-cholest-23-ene-3α,7α,12α-triol: Synthesis of substrates for studies of cholesterol side-chain oxidation;Lipids;1999-04
3. Rapid hydrogenation of unsaturated sterols and bile alcohols using microwaves;Steroids;1997-05
4. A Simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters;Synthetic Communications;1983-12
5. Identification of 5α-stanols in patients with sitosterolemia and xanthomatosis: stereochemistry of the protonolysis of steroidal organoboranes.;Steroids;1982-08
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