Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation-Reference-Cited by-同舟云学术

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Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

Published:2001-04 Issue:8 Volume:11 Page:608-613
ISSN:0960-9822
Container-title:Current Biology
language:en
Short-container-title:Current Biology

Author:

Strutt H.,Thomas C.,Nakano Y.,Stark D.,Neave B.,Taylor A.M.,Ingham P.W.

Publisher

Elsevier BV

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

Reference30 articles.

1. Transducing hedgehog;Ingham;EMBO J,1998

2. Dual roles for Patched in sequestering and transducing Hedgehog;Chen;Cell,1996

3. Subcellular localisation of the segment polarity protein Patched suggests an interaction with the Wingless reception complex in Drosophila embryos;Capdevila;Development,1994

4. Contrasting distributions of Ppatched and Hedgehog proteins in the Drosophila embryo;Taylor;Mech Dev,1993

5. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion;Bellaiche;Nature,1998

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1. Smad4 regulates TGF-β1-mediated hedgehog activation to promote epithelial-to-mesenchymal transition in pancreatic cancer cells by suppressing Gli1 activity;Computational and Structural Biotechnology Journal;2024-12

2. Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability;Cells;2024-01-21

3. Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in Drosophila wing development;Science Signaling;2023-10-17

4. Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability;2022-09-24

5. Patched-Related Is Required for Proper Development of Embryonic Drosophila Nervous System;Frontiers in Neuroscience;2022-08-23

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